pip4k2aa

ID

ZDB-GENE-080721-18

Name

phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a

Symbol

pip4k2aa Nomenclature History

Previous Names

pip4k2a
zgc:194746
zgc:194777

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity. Acts upstream of or within regulation of muscle organ development. Predicted to be located in lysosome and nucleus. Predicted to be active in plasma membrane. Is expressed in brain; central nervous system; eye; pectoral fin; and somite. Orthologous to human PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from Elouarrat et al., 2013

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pip4k2aa Human Ortholog

No data available

Associated With pip4k2aa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002498	Phosphatidylinositol-4-phosphate 4/5-kinase, core
Family	IPR023610	Phosphatidylinositol-4/5-phosphate 5/4-kinase
Homologous_superfamily	IPR027483	Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily
Homologous_superfamily	IPR027484	Phosphatidylinositol-4-phosphate 5-kinase, N-terminal