ZFIN Gene: prdm16

ZFIN ID: ZDB-GENE-080613-2

ZFIN ID: ZDB-GENE-080613-2

Gene Name:

PR domain containing 16

Gene Symbol:

prdm16

Sequence Ontology ID :

SO:0000704

Previous Names:

fc09g08, wu:fc09g08 (1)

Location:

Chr: 8 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in several processes, including cardiac muscle cell proliferation; embryonic cranial skeleton morphogenesis; ...

GENE EXPRESSION
All Expression Data:	5 figures from 4 publications
Wild-type Stages, Structures:	Segmentation:5-9 somites (11.66h-14.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
	brain cranial ganglion diencephalon heart hindbrain hindbrain neural rod neurocranium olfactory placode pectoral fin pectoral fin bud peripheral olfactory organ pronephric duct stomodeum telencephalon whole organism
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
la016416Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la016417Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la026615Tg	Transgenic Insertion	Unknown	Unknown	DNA
la026616Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la026617Tg	Transgenic Insertion	Unknown	Unknown	DNA
la029501Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
sa14438	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa14462	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa31682	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

PHENOTYPE

Data:	5 figures from 3 publications
Observed in:	cardiac muscle cell cell proliferation involved in heart morphogenesis ceratohyal cartilage ethmoid cartilage heart heart contraction hematopoietic stem cell differentiation Meckel's cartilage neurocranial trabecula neurocranium palatoquadrate cartilage ventral wall of dorsal aorta hematopoietic stem cell ventral wall of dorsal aorta

DISEASE ASSOCIATED WITH prdm16 HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
	Cardiomyopathy, dilated, 1LL	615373
	Left ventricular noncompaction 8	615373

DISEASE ASSOCIATED WITH prdm16 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cardiac conduction (more)
Molecular Function	metal ion binding (more)

GO Terms (all 10)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR013087 (1) InterPro:IPR036236 (1)	PROSITE:PS00028 (1) PROSITE:PS50157 (1)	Pfam:PF00096 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	si:ch211-263k4.2-202 (1)	2783	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM prdm16 No data available

MARKER RELATIONSHIPS

prdm16Contained in:	[BAC] DKEY-149F22 (order this)
prdm16Encodes:	[EST] fc09g08

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:XM_001922892 (1)		Select Tool ZFIN BLAST NCBI BLAST MegaBLAST Ensembl UCSC BLAT
Genomic	GenBank:CR847782 (1)	81735bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A5XCD6 (1)	153aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:105603 (1)

Sequence Information (all 48)

OTHER prdm16 GENE PAGES

Alliance (1)

Gene:796720 (1)

VEGA:OTTDARG00000027042 (1)

ORTHOLOGY for prdm16 (Chr: 8)

CITATIONS (24)

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