Gene
prdm16
- ID
- ZDB-GENE-080613-2
- Name
- PR domain containing 16
- Symbol
- prdm16 Nomenclature History
- Previous Names
-
- fc09g08
- si:ch211-263k4.2
- wu:fc09g08 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable chromatin insulator sequence binding activity. Acts upstream of or within several processes, including Wnt signalosome assembly; cardiac muscle cell proliferation; and skeletal system development. Predicted to be located in nucleus. Predicted to be active in chromosome. Is expressed in several structures, including head; hindbrain neural rod; nervous system; pectoral fin bud; and pronephric duct. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1LL. Orthologous to human PRDM16 (PR/SET domain 16).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 1LL | Alliance | Cardiomyopathy, dilated, 1LL | 615373 |
| dilated cardiomyopathy 1LL | Alliance | Left ventricular noncompaction 8 | 615373 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001214 | SET domain |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Domain | IPR044410 | PRDM16, PR/SET domain |
| Family | IPR050331 | Zinc finger |
| Family | IPR050636 | C2H2-type zinc finger domain-containing protein |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
| Homologous_superfamily | IPR046341 | SET domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C2H2-type zinc finger domain-containing protein | PRDM16, PR/SET domain | SET domain | SET domain superfamily | Zinc finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BEM7 | InterPro | 1302 | |||||||
| UniProtKB:A0A8M9QJ45 | InterPro | 1180 | |||||||
| UniProtKB:A0A8M3BC36 | InterPro | 1297 | |||||||
| UniProtKB:A0A8M9Q420 | InterPro | 1332 | |||||||
| UniProtKB:A0A8M9PRJ8 | InterPro | 1335 | |||||||
| UniProtKB:A0A8M1QVB6 | InterPro | 1298 | |||||||
| UniProtKB:A0A8M9QEA0 | InterPro | 1336 | |||||||
| UniProtKB:A0A8M9QA80 | InterPro | 1238 | |||||||
| UniProtKB:A0A8M2BES0 | InterPro | 1308 | |||||||
| UniProtKB:A0AB32TUY5 | InterPro | 1328 | |||||||
| UniProtKB:A0AB32TWU5 | InterPro | 1189 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-263k4.2-201
(1)
|
Ensembl | 2,727 nt | ||
| mRNA |
si:ch211-263k4.2-202
(1)
|
Ensembl | 2,783 nt | ||
| mRNA |
si:ch211-263k4.2-203
(1)
|
Ensembl | 645 nt |
Interactions and Pathways
No data available
Plasmids
No data available