Gene
mmrn2a
- ID
- ZDB-GENE-080424-3
- Name
- multimerin 2a
- Symbol
- mmrn2a Nomenclature History
- Previous Names
-
- si:ch211-134m17.7
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to be located in extracellular region. Is expressed in cardiovascular system; fin bud; floor plate; gut; and presumptive neural retina. Orthologous to human MMRN2 (multimerin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Milanetto et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa548 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa22281 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa22282 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa45484 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | C1q domain | Collagen/C1q domain-containing | EMI domain | Tumour necrosis factor-like domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B319 | InterPro | 1033 | ||||
| UniProtKB:A0A8M1NTG9 | InterPro | 1057 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mmrn2a-202
(1)
|
Ensembl | 3,778 nt | ||
| ncRNA |
mmrn2a-002
(1)
|
Ensembl | 827 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-134M17 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001145706 (1) | 4484 nt | ||
| Genomic | GenBank:BX005174 (1) | 178371 nt | ||
| Polypeptide | UniProtKB:A0A8M1NTG9 (1) | 1057 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Hu, Y.L., Pan, X.M., Xiang, L.X., and Shao, J.Z. (2010) Characterization of C1Q in teleosts: insight into the molecular and functional evolution of C1Q family and classical pathway. The Journal of biological chemistry. 285(37):28777-28786
- Mei, J., and Gui, J. (2008) Bioinformatic identification of genes encoding C1q-domain-containing proteins in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 35(1):17-24
- Milanetto, M., Tiso, N., Braghetta, P., Volpin, D., Argenton, F., and Bonaldo, P. (2008) Emilin genes are duplicated and dynamically expressed during zebrafish embryonic development. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(1):222-232
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