Gene

myo18ab

ID

ZDB-GENE-080423-1

Name

myosin XVIIIA b

Symbol

myo18ab Nomenclature History

Previous Names

myo18a (1)
myo18l1
si:ch211-103e6.2
tiaf1
wu:fb52c07

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Involved in several processes, including Golgi organization; muscle tissue morphogenesis; and striated muscle cell development. Predicted to localize to myosin complex. Is expressed in head; notochord; skeletal muscle cell; and somite. Orthologous to human MYO18A (myosin XVIIIA).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With myo18ab Human Ortholog

No data available

Associated With myo18ab Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR000048	IQ motif, EF-hand binding site
Domain	IPR001478	PDZ domain
Domain	IPR001609	Myosin head, motor domain
Domain	IPR002928	Myosin tail
Domain	IPR004009	Myosin, N-terminal, SH3-like
Domain	IPR036064	Class XVIII myosin, motor domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036034	PDZ superfamily
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily

Domain Details Per Protein

Protein	Length	Class XVIII myosin, motor domain	IQ motif, EF-hand binding site	Kinesin motor domain superfamily	Myosin head, motor domain	Myosin, N-terminal, SH3-like	Myosin tail	PDZ domain	PDZ superfamily	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M9P7A8 InterPro	2252
UniProtKB:A0A8M6YT96 InterPro	2054
UniProtKB:A0A8M9P7B3 InterPro	1636
UniProtKB:A0A8M9NYM9 InterPro	2267
UniProtKB:A0A8M3AHI6 InterPro	2070
UniProtKB:A0A8M9PIP0 InterPro	2069
UniProtKB:A0A8M3APY2 InterPro	2092
UniProtKB:A0A8M9PLN0 InterPro	2207
UniProtKB:A0A8M9PCE1 InterPro	2237
UniProtKB:A0A8M9NYN3 InterPro	1737

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	myo18ab-202 (1) Ensembl	Havana	9522 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	myo18ab-002 (1) Ensembl	Havana	539 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	ottdart00000060038 (1) Ensembl	Havana	565 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations