ZFIN is now using GRCz12tu for Genomic Data
Gene
nr1d4b
- ID
- ZDB-GENE-080403-6
- Name
- nuclear receptor subfamily 1, group D, member 4b
- Symbol
- nr1d4b Nomenclature History
- Previous Names
-
- gb:dq017623
- Reverbgamma-B (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in several processes, including hormone-mediated signaling pathway; intracellular receptor signaling pathway; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription and retinoic acid receptor signaling pathway. Predicted to be active in nucleus. Is expressed in liver and biliary system; nervous system; and pancreatic system.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- dq017623 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR003078 | Retinoic acid receptor |
| Family | IPR050234 | Nuclear hormone receptor family NR1 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nuclear hormone receptor | Nuclear hormone receptor family NR1 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Retinoic acid receptor | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:U3M0S0 | InterPro | 576 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nr1d4b-201
(1)
|
Ensembl | 1,060 nt | ||
| mRNA |
nr1d4b-202
(1)
|
Ensembl | 2,482 nt | ||
| mRNA |
nr1d4b-203
(1)
|
Ensembl | 1,719 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers