Gene

elfn1b

ID

ZDB-GENE-080327-21

Name

extracellular leucine-rich repeat and fibronectin type III domain containing 1b

Symbol

elfn1b Nomenclature History

Previous Names

elfn1 (1)
sc:d0369

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to be located in membrane. Predicted to be active in extracellular matrix and extracellular space. Is expressed in brain and neurons. Used to study schizophrenia. Orthologous to human ELFN1 (extracellular leucine rich repeat and fibronectin type III domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d0369 (16 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Thyme et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With elfn1b Human Ortholog

No data available

Associated With elfn1b Via Experimental Models

Human Disease	Fish	Conditions	Citations
schizophrenia	elfn1b^a217/a217	standard conditions	Thyme et al., 2019

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000483	Cysteine-rich flanking region, C-terminal
Domain	IPR055106	ELFN1/ELFN2, fibronectin type-III domain
Family	IPR050541	Leucine-rich repeat and transmembrane domain-containing protein
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype

Domain Details Per Protein

Protein	Additional Resources	Length	Cysteine-rich flanking region, C-terminal	ELFN1/ELFN2, fibronectin type-III domain	Leucine-rich repeat	Leucine-rich repeat and transmembrane domain-containing protein	Leucine-rich repeat domain superfamily	Leucine-rich repeat, typical subtype
UniProtKB:F1Q7Y5	InterPro	814

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	elfn1b-201 (1) Ensembl	Ensembl		4,282 nt	Select Tool ZFIN BLAST
mRNA	elfn1b-202 (1) Ensembl	Ensembl		2,445 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations