Gene

degs2

ID

ZDB-GENE-080228-1

Name

delta(4)-desaturase, sphingolipid 2

Symbol

degs2 Nomenclature History

Previous Names

im:6909358

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Orthologous to human DEGS2 (delta 4-desaturase, sphingolipid 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6909358 (1 image)
IMAGE:7154669 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With degs2 Human Ortholog

No data available

Associated With degs2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005804	Fatty acid desaturase domain
Domain	IPR013866	Sphingolipid delta4-desaturase, N-terminal
Family	IPR011388	Sphingolipid delta4-desaturase

Domain Details Per Protein

Protein	Length	Fatty acid desaturase domain	Sphingolipid delta4-desaturase	Sphingolipid delta4-desaturase, N-terminal
UniProtKB:F1QW74 InterPro	322

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	degs2-201 (1) Ensembl	Ensembl		1,793 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations