Gene

zmiz1a

ID

ZDB-GENE-080220-27

Name

zinc finger, MIZ-type containing 1a

Symbol

zmiz1a Nomenclature History

Previous Names

zmiz1 (1)
fb80e10
wu:fb80e10
zgc:175159

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to enable SUMO ligase activity and nuclear receptor coactivator activity. Predicted to be involved in protein sumoylation and regulation of transcription by RNA polymerase II. Orthologous to human ZMIZ1 (zinc finger MIZ-type containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from Castillo-Castellanos et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With zmiz1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies	618659

Associated With zmiz1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004181	Zinc finger, MIZ-type
Domain	IPR040797	Zmiz1, N-terminal tetratricopeptide repeat domain
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type

Domain Details Per Protein

Protein	Length	Zinc finger, MIZ-type	Zinc finger, RING/FYVE/PHD-type	Zmiz1, N-terminal tetratricopeptide repeat domain
UniProtKB:A0A8M2B3N1 InterPro	1066
UniProtKB:A0A8M2B372 InterPro	1080
UniProtKB:A9JRY4 InterPro	1024
UniProtKB:A0A8M3BEN7 InterPro	1078
UniProtKB:A0A8M3B818 InterPro	937
UniProtKB:A0A8M2B3T1 InterPro	1068