ZFIN is now using GRCz12tu for Genomic Data
Gene
mknk1
- ID
- ZDB-GENE-080220-11
- Name
- MAPK interacting serine/threonine kinase 1
- Symbol
- mknk1 Nomenclature History
- Previous Names
-
- zgc:171912
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium-dependent protein serine/threonine kinase activity; calcium/calmodulin-dependent protein kinase activity; and calmodulin binding activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK1 (MAPK interacting serine/threonine kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR050205 | Calcium-dependent Serine/Threonine Protein Kinases |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Calcium-dependent Serine/Threonine Protein Kinases | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B2B7 | InterPro | 461 | |||||
| UniProtKB:A0A8M2B223 | InterPro | 490 | |||||
| UniProtKB:F1QJV2 | InterPro | 459 | |||||
| UniProtKB:A0A8M2B1Y9 | InterPro | 488 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers