ZFIN ID: ZDB-GENE-080219-25
Gene Name: zgc:172053
Gene Symbol: zgc:172053    Nomenclature History

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Previous Name: si:ch211-125e6.7 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have signaling receptor activity. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to several human genes including REG1A (regenerating family member 1 alpha); REG1B (regenerating family member 1 beta); and REG3A (regenerating family member 3 alpha).
Genome Resources: Alliance (1),  Gene:100002541 (1),  Ensembl(GRCz11):ENSDARG00000038321 (2)

Nomenclature Note: This gene is characterized by full length cDNAs isolated as part of the Zebrafish Gene Collection (ZGC). When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix `zgc:' indicates that this gene is represented by cDNAs generated by the ZGC project.

GENE EXPRESSION
All Expression Data: Fig. 2 from Lam et al., 2011
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30921 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH zgc:172053 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH zgc:172053 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process biological_process (more)
    Cellular Component cellular_component (more)
    Molecular Function signaling receptor activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zgc:172053-201 (1)    Ensembl 696
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zgc:172053 No data available
    MARKER RELATIONSHIPS
    zgc:172053 Contained in: [BAC] CH211-125E6 (1)
    zgc:172053 Encodes: [cDNA] MGC:172053 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001111242 (1) 670 nt
    Genomic GenBank:BX511259 (1) 182412 nt
    Select Tool
    Polypeptide UniProtKB:A9JRA9 (1) 151 aa
    Sequence Information (all 10)
    ORTHOLOGY for zgc:172053 ( Chr: 9 )
    CITATIONS (19)