Gene
dis3
- ID
- ZDB-GENE-080213-3
- Name
- DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
- Symbol
- dis3 Nomenclature History
- Previous Names
-
- wu:fb08g12
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable 3'-5'-RNA exonuclease activity and endonuclease activity. Predicted to be involved in nuclear mRNA surveillance of mRNA 3'-end processing and rRNA catabolic process. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Orthologous to human DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR022966 | Ribonuclease II/R, conserved site |
| Domain | IPR001900 | Ribonuclease II/R |
| Domain | IPR002716 | PIN domain |
| Domain | IPR033770 | Exosome complex exonuclease RRP44, S1 domain |
| Domain | IPR033771 | Rrp44-like cold shock domain |
| Domain | IPR041505 | Dis3-like cold-shock domain 2 |
| Family | IPR050180 | RNR Ribonuclease |
| Homologous_superfamily | IPR012340 | Nucleic acid-binding, OB-fold |
| Homologous_superfamily | IPR029060 | PIN-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Dis3-like cold-shock domain 2 | Exosome complex exonuclease RRP44, S1 domain | Nucleic acid-binding, OB-fold | PIN domain | PIN-like domain superfamily | Ribonuclease II/R | Ribonuclease II/R, conserved site | RNR Ribonuclease | Rrp44-like cold shock domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7FE01
|
950 |
Interactions and Pathways
No data available
Plasmids
No data available