Gene
egr4
- ID
- ZDB-GENE-080204-90
- Name
- early growth response 4
- Symbol
- egr4 Nomenclature History
- Previous Names
-
- zgc:175128
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in brain. Used to study congenital heart disease. Orthologous to human EGR4 (early growth response 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| congenital heart disease | AB + MO1-egr4 | standard conditions | Liu et al., 2022 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|
|
UniProtKB:A9JTG0
|
352 |
Interactions and Pathways
No data available
Plasmids
No data available