Gene

hbegfa

ID
ZDB-GENE-080204-119
Name
heparin-binding EGF-like growth factor a
Symbol
hbegfa Nomenclature History
Previous Names
  • zgc:175091
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Involved in retina development in camera-type eye and sensory epithelium regeneration. Predicted to localize to extracellular space. Is expressed in retina. Human ortholog(s) of this gene implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. Orthologous to human HBEGF (heparin binding EGF like growth factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from El-Brolosy et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hbegfa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Diphtheria, susceptibility to}
Associated With hbegfa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Family IPR015497 Epidermal growth factor receptor ligand
Domain Details Per Protein
Protein Length EGF-like domain Epidermal growth factor receptor ligand
UniProtKB:A9JRW9 230
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations