Gene
prkd1
- ID
- ZDB-GENE-080131-1
- Name
- protein kinase D1
- Symbol
- prkd1 Nomenclature History
- Previous Names
-
- PKD1 (1)
- si:dkeyp-47g2.1
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity; calcium-dependent protein kinase C activity; and metal ion binding activity. Acts upstream of or within regulation of angiogenesis and regulation of lymphangiogenesis. Predicted to be located in cytoplasm and membrane. Orthologous to human PRKD1 (protein kinase D1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Hollenbach et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Hollenbach et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Congenital heart defects and ectodermal dysplasia | 617364 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR020454 | Diacylglycerol/phorbol-ester binding |
| Family | IPR015727 | Protein kinase C mu-related |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Length | C1-like domain superfamily | Diacylglycerol/phorbol-ester binding | PH-like domain superfamily | Pleckstrin homology domain | Protein kinase, ATP binding site | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Protein kinase C mu-related | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PPI9
|
878 | ||||||||||
|
UniProtKB:X1WHC7
|
886 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-prkd1 | polyclonal | Rabbit |
|
Santa Cruz Biotechnology, Inc.
|
2 |
Plasmids
No data available