Gene

arhgap45b

ID

ZDB-GENE-071213-2

Name

Rho GTPase activating protein 45b

Symbol

arhgap45b Nomenclature History

Previous Names

arhgap45
hmha1
hmha1b
si:ch73-243b8.4

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity. Predicted to act upstream of or within intracellular signal transduction. Predicted to be active in membrane. Orthologous to human ARHGAP45 (Rho GTPase activating protein 45).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Gomez et al., 2012

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arhgap45b Human Ortholog

No data available

Associated With arhgap45b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000198	Rho GTPase-activating protein domain
Domain	IPR001060	FCH domain
Domain	IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain	IPR031160	F-BAR domain
Family	IPR051025	Rho GTPase-activating
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR027267	AH/BAR domain superfamily
Homologous_superfamily	IPR046349	C1-like domain superfamily

Domain Details Per Protein

Protein	Length	AH/BAR domain superfamily	C1-like domain superfamily	F-BAR domain	FCH domain	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Rho GTPase-activating	Rho GTPase-activating protein domain	Rho GTPase activation protein
UniProtKB:A0A8M2BHU6 InterPro	1136
UniProtKB:A0A8M2BI97 InterPro	1134
UniProtKB:A0A8M2BHV5 InterPro	1135
UniProtKB:A0A8M2BHU4 InterPro	1135
UniProtKB:A0A8N7USS5 InterPro	1127

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	hmha1b-202 (1) Ensembl	Ensembl		2,728 nt	Select Tool ZFIN BLAST
mRNA	si:ch73-243b8.4-201 (1) Ensembl	Ensembl		1,483 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations