Gene
flii
- ID
- ZDB-GENE-071212-3
- Name
- FLII actin remodeling protein
- Symbol
- flii Nomenclature History
- Previous Names
-
- im:7141769
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Involved in sarcomere organization. Is expressed in myotome. Orthologous to human FLII (FLII actin remodeling protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7141769 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Naganawa et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cardiomyopathy, dilated, 2J | 620635 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR007123 | Gelsolin-like domain |
| Family | IPR007122 | Villin/Gelsolin |
| Homologous_superfamily | IPR029006 | ADF-H/Gelsolin-like domain superfamily |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Homologous_superfamily | IPR036180 | Gelsolin-like domain superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
| Repeat | IPR025875 | Leucine rich repeat 4 |
Domain Details Per Protein
| Protein | Length | ADF-H/Gelsolin-like domain superfamily | Gelsolin-like domain | Gelsolin-like domain superfamily | Leucine-rich repeat | Leucine rich repeat 4 | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype | Villin/Gelsolin |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F8WK50
|
1259 |
Interactions and Pathways
No data available
Plasmids
No data available