Gene

ulk1b

ID

ZDB-GENE-071203-2

Name

unc-51 like autophagy activating kinase 1

Symbol

ulk1b Nomenclature History

Previous Names

ulk1
si:dkey-11o18.7

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including autophagosome assembly; axon extension; and protein autophosphorylation. Predicted to localize to cytosol; membrane; and phagophore assembly site. Is expressed in liver. Orthologous to human ULK1 (unc-51 like autophagy activating kinase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ulk1b Human Ortholog

No data available

Associated With ulk1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR022708	Serine/threonine-protein kinase Atg1-like, tMIT domain
Domain	IPR048941	ATG1-like, MIT domain 2
Family	IPR045269	Serine/threonine-protein kinase Atg1-like
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Length	ATG1-like, MIT domain 2	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site	Serine/threonine-protein kinase Atg1-like	Serine/threonine-protein kinase Atg1-like, tMIT domain
UniProtKB:A0A8M2B823 InterPro	1010
UniProtKB:E9QIB7 InterPro	1011
UniProtKB:A0A8M9PIT5 InterPro	1010

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ulk1b-201 (1) Ensembl	Ensembl	3,573 nt	Select Tool
ncRNA	ulk1b-002 (1) Ensembl	Ensembl	502 nt	Select Tool
ncRNA	ulk1b-003 (1) Ensembl	Ensembl	769 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations