Gene

nkd2a

ID
ZDB-GENE-071130-1
Name
NKD inhibitor of WNT signaling pathway 2a
Symbol
nkd2a Nomenclature History
Previous Names
  • nkd2 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Involved in several processes, including Kupffer's vesicle development; Spemann organizer formation; and negative regulation of canonical Wnt signaling pathway. Predicted to localize to cytoplasm. Is expressed in blastoderm; blastodisc; brain; and tail bud. Orthologous to human NKD2 (NKD inhibitor of WNT signaling pathway 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nkd2a Human Ortholog
No data available
Associated With nkd2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR002048 EF-hand domain
Family IPR040140 Protein naked cuticle-like
Homologous_superfamily IPR011992 EF-hand domain pair
Domain Details Per Protein
Protein Length EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair Protein naked cuticle-like
UniProtKB:F1QI44
UniProtKB:A4ZNR4 409
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nkd2a-201 (1) Ensembl 1,432 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-nkd2a polyclonal Rabbit
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations