Gene
nfkbiz
- ID
- ZDB-GENE-071024-1
- Name
- nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
- Symbol
- nfkbiz Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity and POU domain binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in membrane. Predicted to be active in nucleus. Orthologous to human NFKBIZ (NFKB inhibitor zeta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | OCA domain |
|---|---|---|---|---|---|
| UniProtKB:A0A8M9PWV3 | InterPro | 389 | |||
| UniProtKB:A0A8M9Q7W9 | InterPro | 524 | |||
| UniProtKB:A0A8M9PJF3 | InterPro | 510 |
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- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nfkbiz-201
(1)
|
Ensembl | 1,505 nt | ||
| mRNA |
nfkbiz-203
(1)
|
Ensembl | 1,799 nt | ||
| ncRNA |
nfkbiz-003
(1)
|
Ensembl | 493 nt | ||
| ncRNA |
nfkbiz-004
(1)
|
Ensembl | 787 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | Fosmid | ZFOS-1597F10 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_021475911 (1) | 2332 nt | ||
| Genomic | GenBank:CU651657 (1) | 44124 nt | ||
| Polypeptide | UniProtKB:A0A8M9Q7W9 (1) | 524 aa |
- Geng, Y., Zhang, T., Alonzo, I.G., Godar, S.C., Yates, C., Pluimer, B.R., Harrison, D.L., Nath, A.K., Yeh, J.J., Drummond, I.A., Bortolato, M., Peterson, R.T. (2022) Top2a promotes the development of social behavior via PRC2 and H3K27me3. Science advances. 8:eabm7069
- Sun, Y., Zhang, B., Luo, L., Shi, D.L., Wang, H., Cui, Z., Huang, H., Cao, Y., Shu, X., Zhang, W., Zhou, J., Li, Y., Du, J., Zhao, Q., Chen, J., Zhong, H., Zhong, T.P., Li, L., Xiong, J.W., Peng, J., Xiao, W., Zhang, J., Yao, J., Yin, Z., Mo, X., Peng, G., Zhu, J., Chen, Y., Zhou, Y., Liu, D., Pan, W., Zhang, Y., Ruan, H., Liu, F., Zhu, Z., Meng, A., ZAKOC Consortium (2019) Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome research. 30(1):118-26
- Yoder, J.A., Orcutt, T.M., Traver, D., and Litman, G.W. (2007) Structural characteristics of zebrafish orthologs of adaptor molecules that associate with transmembrane immune receptors. Gene. 401(1-2):154-164
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