Gene

fdx1

ID

ZDB-GENE-071015-2

Name

ferredoxin 1

Symbol

fdx1 Nomenclature History

Previous Names

im:6907289

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable 2 iron, 2 sulfur cluster binding activity; electron transfer activity; and metal ion binding activity. Acts upstream of or within negative regulation of epiboly involved in gastrulation with mouth forming second. Predicted to be active in mitochondrion. Is expressed in brain; digestive system; heart; and pleuroperitoneal region. Orthologous to human FDX1 (ferredoxin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6907289 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Griffin et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fdx1 Human Ortholog

No data available

Associated With fdx1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018298	Adrenodoxin, iron-sulphur binding site
Domain	IPR001041	2Fe-2S ferredoxin-type iron-sulfur binding domain
Family	IPR001055	Adrenodoxin-like
Homologous_superfamily	IPR012675	Beta-grasp domain superfamily
Homologous_superfamily	IPR036010	2Fe-2S ferredoxin-like superfamily

Domain Details Per Protein

Protein	Length	2Fe-2S ferredoxin-like superfamily	2Fe-2S ferredoxin-type iron-sulfur binding domain	Adrenodoxin, iron-sulphur binding site	Adrenodoxin-like	Beta-grasp domain superfamily
UniProtKB:E7F7J1 InterPro	175

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	fdx1-201 (1) Ensembl	Ensembl	730 nt	Select Tool ZFIN BLAST
aberrant processed transcript	fdx1-203 (1) Ensembl	Ensembl	927 nt	Select Tool ZFIN BLAST
aberrant processed transcript	fdx1-204 (1) Ensembl	Ensembl	870 nt	Select Tool ZFIN BLAST
mRNA	fdx1-202 (1) Ensembl	Ensembl	952 nt	Select Tool ZFIN BLAST
ncRNA	fdx1-003 (1) Ensembl	Ensembl	474 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations