Gene
hpdl
- ID
- ZDB-GENE-071004-50
- Name
- 4-hydroxyphenylpyruvate dioxygenase-like
- Symbol
- hpdl Nomenclature History
- Previous Names
-
- fj39d06
- wu:fj39d06
- zgc:171978 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have 4-hydroxyphenylpyruvate dioxygenase activity and metal ion binding activity. Predicted to be involved in aromatic amino acid family metabolic process and oxidation-reduction process. Orthologous to human HPDL (4-hydroxyphenylpyruvate dioxygenase like).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
hereditary spastic paraplegia 83 | Alliance | Spastic paraplegia 83, autosomal recessive | 619027 |
Neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities | 619026 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR004360 | Glyoxalase/fosfomycin resistance/dioxygenase domain |
Domain | IPR037523 | Vicinal oxygen chelate (VOC) domain |
Domain | IPR041735 | 4-hydroxyphenylpyruvate dioxygenase, C-terminal |
Domain | IPR041736 | 4-hydroxyphenylpyruvate dioxygenase, N-terminal |
Family | IPR005956 | 4-hydroxyphenylpyruvate dioxygenase |
Homologous_superfamily | IPR029068 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
Domain Details Per Protein
Protein | Length | 4-hydroxyphenylpyruvate dioxygenase | 4-hydroxyphenylpyruvate dioxygenase, C-terminal | 4-hydroxyphenylpyruvate dioxygenase, N-terminal | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/fosfomycin resistance/dioxygenase domain | Vicinal oxygen chelate (VOC) domain |
---|---|---|---|---|---|---|---|
UniProtKB:A7MC29
|
420 | ||||||
UniProtKB:E7FH29
|
420 |
Interactions and Pathways
No data available
Plasmids
No data available