Gene

atf4b

ID
ZDB-GENE-070928-23
Name
activating transcription factor 4b
Symbol
atf4b Nomenclature History
Previous Names
  • atf4b2
  • sb:eu681
  • wu:fb08f07
  • zgc:171702
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in cytoplasm. Predicted to be part of ATF1-ATF4 transcription factor complex and ATF4-CREB1 transcription factor complex. Predicted to be active in nucleus. Is expressed in several structures, including brain; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human ATF4 (activating transcription factor 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atf4b Human Ortholog
No data available
Associated With atf4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004827 Basic-leucine zipper domain
Homologous_superfamily IPR046347 Basic-leucine zipper domain superfamily
Domain Details Per Protein
Protein Length Basic-leucine zipper domain Basic-leucine zipper domain superfamily
UniProtKB:A7MBV8 425
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA atf4b-201 (1) Ensembl 1,981 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations