Gene
atf4b
- ID
- ZDB-GENE-070928-23
- Name
- activating transcription factor 4b
- Symbol
- atf4b Nomenclature History
- Previous Names
-
- atf4b2
- sb:eu681
- wu:fb08f07
- zgc:171702
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in cytoplasm. Predicted to be part of ATF1-ATF4 transcription factor complex and ATF4-CREB1 transcription factor complex. Predicted to be active in nucleus. Is expressed in several structures, including brain; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human ATF4 (activating transcription factor 4).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 12 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu681 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Basic-leucine zipper domain | Basic-leucine zipper domain superfamily |
---|---|---|---|
UniProtKB:A7MBV8
|
425 |
Interactions and Pathways
No data available
Plasmids
No data available