ZFIN is now using GRCz12tu for Genomic Data
Gene
kiss1ra
- ID
- ZDB-GENE-070912-521
- Name
- KISS1 receptor a
- Symbol
- kiss1ra Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway and positive regulation of hormone secretion. Located in cell surface and cytoplasm. Is expressed in several structures, including brain; fat cell; head; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in central precocious puberty 1; hypogonadism; and hypogonadotropic hypogonadism 8 with or without anosmia. Orthologous to human KISS1R (KISS1 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| central precocious puberty 1 | Alliance | ?Precocious puberty, central, 1 | 176400 |
| hypogonadotropic hypogonadism 8 with or without anosmia | Alliance | Hypogonadotropic hypogonadism 8 with or without anosmia | 614837 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | KiSS-1 peptide receptor |
|---|---|---|---|---|---|
| UniProtKB:B0F101 | InterPro | 253 | |||
| UniProtKB:F1R5R4 | InterPro | 366 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kiss1ra-201
(1)
|
Ensembl | 1,101 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-kiss1ra | polyclonal | Rabbit |
|
1 |
Plasmids
No data available
- Genome Browsers