Gene

igf2bp2a

ID
ZDB-GENE-070912-44
Name
insulin-like growth factor 2 mRNA binding protein 2a
Symbol
igf2bp2a Nomenclature History
Previous Names
  • igf2bp2
  • si:ch211-125m20.1
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in nervous system development; regulation of RNA metabolic process; and regulation of gene expression. Predicted to act upstream of or within mRNA transport. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human IGF2BP2 (insulin like growth factor 2 mRNA binding protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from O'Hare et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With igf2bp2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
type 2 diabetes mellitus Alliance {Diabetes mellitus, noninsulin-dependent, susceptibility to} 125853
Associated With igf2bp2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR004087 K Homology domain
Domain IPR004088 K Homology domain, type 1
Domain IPR034843 IGF2BP2, RNA recognition motif 1
Family IPR028743 Insulin-like growth factor 2 mRNA-binding protein 2
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Homologous_superfamily IPR036612 K Homology domain, type 1 superfamily
Domain Details Per Protein
Protein Length IGF2BP2, RNA recognition motif 1 Insulin-like growth factor 2 mRNA-binding protein 2 K Homology domain K Homology domain, type 1 K Homology domain, type 1 superfamily Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:A0A2R8RHK1 453
UniProtKB:A0A2R8RTZ0 388
UniProtKB:A0A2R8QC11 261
UniProtKB:A0A0B4J1B0 607
UniProtKB:A9JSV1 261
UniProtKB:A0A2R8Q8A4 542
UniProtKB:A9C3V8 606
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations