Gene

pip4k2ab

ID

ZDB-GENE-070912-272

Name

phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b

Symbol

pip4k2ab Nomenclature History

Previous Names

si:ch211-279l9.5

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable 1-phosphatidylinositol-5-phosphate 4-kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within phosphatidylinositol metabolic process and phosphorylation. Predicted to be located in lysosome; membrane; and nucleus. Predicted to be active in plasma membrane. Orthologous to human PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Elouarrat et al., 2013

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pip4k2ab Human Ortholog

No data available

Associated With pip4k2ab Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002498	Phosphatidylinositol-4-phosphate 4/5-kinase, core
Family	IPR023610	Phosphatidylinositol-4/5-phosphate 5/4-kinase
Homologous_superfamily	IPR027483	Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily
Homologous_superfamily	IPR027484	Phosphatidylinositol-4-phosphate 5-kinase, N-terminal

Domain Details Per Protein

Protein	Length	Phosphatidylinositol-4/5-phosphate 5/4-kinase	Phosphatidylinositol-4-phosphate 4/5-kinase, core	Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily	Phosphatidylinositol-4-phosphate 5-kinase, N-terminal
UniProtKB:A0A8M2BAK4 InterPro	445
UniProtKB:B0UXW0 InterPro	413

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pip4k2ab-201 (1) Ensembl	Ensembl	1,011 nt	Select Tool ZFIN BLAST
mRNA	pip4k2ab-202 (1) Ensembl	Ensembl	532 nt	Select Tool ZFIN BLAST
mRNA	pip4k2ab-203 (1) Ensembl	Ensembl	2,253 nt	Select Tool ZFIN BLAST
ncRNA	pip4k2ab-002 (1) Ensembl	Ensembl	463 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations