Gene

rasal2

ID

ZDB-GENE-070912-180

Name

RAS protein activator like 2

Symbol

rasal2 Nomenclature History

Previous Names

fc75a03
si:ch211-198i20.2
wu:fc75a03

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity. Predicted to be involved in regulation of GTPase activity and signal transduction. Orthologous to human RASAL2 (RAS protein activator like 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rasal2 Human Ortholog

No data available

Associated With rasal2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR023152	Ras GTPase-activating protein, conserved site
Domain	IPR000008	C2 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR001936	Ras GTPase-activating domain
Domain	IPR021887	Disabled homolog 2-interacting protein, C-terminal domain
Family	IPR039360	Ras GTPase-activating protein
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR035892	C2 domain superfamily

Domain Details Per Protein

Protein	Length	C2 domain	C2 domain superfamily	Disabled homolog 2-interacting protein, C-terminal domain	Pleckstrin homology domain	Ras GTPase-activating domain	Ras GTPase-activating protein	Ras GTPase-activating protein, conserved site	Rho GTPase activation protein
UniProtKB:A0A8M2BIN1 InterPro	1174
UniProtKB:A0A8M2BIR4 InterPro	1432
UniProtKB:F1QX32 InterPro	1343
UniProtKB:A0A8M2BIM6 InterPro	1425
UniProtKB:A0A8M2BJ40 InterPro	1177

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rasal2-201 (1) Ensembl	Ensembl	4,867 nt	Select Tool ZFIN BLAST
mRNA	rasal2-202 (1) Ensembl	Ensembl	5,146 nt	Select Tool
mRNA	rasal2-203 (1) Ensembl	Ensembl	575 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations