Gene

adam23a

ID

ZDB-GENE-070810-2

Name

ADAM metallopeptidase domain 23a

Symbol

adam23a Nomenclature History

Previous Names

wu:fj40f01
wu:fq14a08

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Predicted to be active in presynaptic membrane. Is expressed in central nervous system. Orthologous to human ADAM23 (ADAM metallopeptidase domain 23).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adam23a Human Ortholog

No data available

Associated With adam23a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR001590	Peptidase M12B, ADAM/reprolysin
Domain	IPR001762	Disintegrin domain
Domain	IPR002870	Peptidase M12B, propeptide
Domain	IPR006586	ADAM, cysteine-rich domain
Domain	IPR034027	Reprolysin domain, adamalysin-type
Homologous_superfamily	IPR024079	Metallopeptidase, catalytic domain superfamily
Homologous_superfamily	IPR036436	Disintegrin domain superfamily

Domain Details Per Protein

Protein	Length	ADAM, cysteine-rich domain	Disintegrin domain	Disintegrin domain superfamily	EGF-like domain	Metallopeptidase, catalytic domain superfamily	Peptidase M12B, ADAM/reprolysin	Peptidase M12B, propeptide	Reprolysin domain, adamalysin-type
UniProtKB:A0A8M2BD47 InterPro	785
UniProtKB:F8W3T1 InterPro	785

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	adam23a-201 (1) Ensembl	Ensembl	2,703 nt	Select Tool ZFIN BLAST
mRNA	adam23a-202 (1) Ensembl	Ensembl	3,194 nt	Select Tool ZFIN BLAST
mRNA	adam23a-203 (1) Ensembl	Ensembl	2,148 nt	Select Tool ZFIN BLAST
mRNA	adam23a-204 (1) Ensembl	Ensembl	2,100 nt	Select Tool ZFIN BLAST
mRNA	adam23a-205 (1) Ensembl	Ensembl	2,148 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations