ZFIN is now using GRCz12tu for Genomic Data
Gene
smarca1
- ID
- ZDB-GENE-070705-296
- Name
- SNF2 related chromatin remodeling ATPase 1
- Symbol
- smarca1 Nomenclature History
- Previous Names
-
- si:dkey-148b12.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA binding activity; chromatin binding activity; and nucleosome array spacer activity. Acts upstream of or within neural plate anterior/posterior regionalization and primitive erythrocyte differentiation. Predicted to be active in chromatin and nucleus. Orthologous to human SMARCA1 (SNF2 related chromatin remodeling ATPase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2488 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Huang et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000330 | SNF2, N-terminal |
| Domain | IPR001005 | SANT/Myb domain |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR015194 | ISWI, HAND domain |
| Domain | IPR015195 | SLIDE domain |
| Domain | IPR017884 | SANT domain |
| Domain | IPR049730 | SNF2/RAD5-like, C-terminal helicase domain |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036306 | ISWI, HAND domain superfamily |
| Homologous_superfamily | IPR038718 | SNF2-like, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | Homedomain-like superfamily | ISWI, HAND domain | ISWI, HAND domain superfamily | P-loop containing nucleoside triphosphate hydrolase | SANT domain | SANT/Myb domain | SLIDE domain | SNF2-like, N-terminal domain superfamily | SNF2, N-terminal | SNF2/RAD5-like, C-terminal helicase domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A5WUY4 | InterPro | 1036 | ||||||||||||
| UniProtKB:A0A8M2BCD5 | InterPro | 1015 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
smarca1-201
(1)
|
Ensembl | 3,843 nt | ||
| ncRNA |
smarca1-002
(1)
|
Ensembl | 770 nt | ||
| ncRNA |
smarca1-003
(1)
|
Ensembl | 518 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers