Gene
scn4ba
- ID
- ZDB-GENE-070615-18
- Name
- sodium channel, voltage-gated, type IV, beta a
- Symbol
- scn4ba Nomenclature History
- Previous Names
-
- scn4b.1 (1)
- zgc:165389
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable sodium channel regulator activity and transmembrane transporter binding activity. Predicted to be involved in cardiac conduction; cardiac muscle cell action potential; and regulation of ventricular cardiac muscle cell membrane repolarization. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated sodium channel complex. Predicted to be active in plasma membrane. Is expressed in atrium; brain; cardiac ventricle; eye; and musculature system. Human ortholog(s) of this gene implicated in long QT syndrome 10. Orthologous to human SCN4B (sodium voltage-gated channel beta subunit 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| long QT syndrome 10 | Alliance | Atrial fibrillation, familial, 17 | 611819 |
| long QT syndrome 10 | Alliance | Long QT syndrome 10 | 611819 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR000920 | Myelin P0 protein-related |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain | Myelin P0 protein-related |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q06W26 | InterPro | 232 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
scn4ba-201
(1)
|
Ensembl | 2,072 nt |
Interactions and Pathways
No data available
Plasmids
No data available