Gene
apln
- ID
- ZDB-GENE-070521-8
- Name
- apelin
- Symbol
- apln Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Enables apelin receptor binding activity. Acts upstream of or within with a positive effect on determination of heart left/right asymmetry and determination of liver left/right asymmetry. Acts upstream of or within several processes, including cell migration involved in mesendoderm migration; circulatory system development; and mesodermal cell migration. Predicted to be located in extracellular space. Is expressed in several structures, including axial chorda mesoderm; axis; cardiovascular system; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human APLN (apelin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR026155 | Apelin |
Domain Details Per Protein
| Protein | Length | Apelin |
|---|---|---|
|
UniProtKB:Q4TTN8
|
77 |
Interactions and Pathways
No data available
Plasmids
No data available