Gene

jam3a

ID
ZDB-GENE-070424-177
Name
junctional adhesion molecule 3a
Symbol
jam3a Nomenclature History
Previous Names
  • jamc2 (1)
  • si:ch211-277g22.3
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in cell adhesion. Predicted to localize to integral component of membrane. Is expressed in brain; lateral line primordium; and neural tube. Orthologous to human JAM3 (junctional adhesion molecule 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Powell et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With jam3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hemorrhagic destruction of the brain, subependymal calcification, and cataracts 613730
Associated With jam3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR007110 Immunoglobulin-like domain
Family IPR042974 Junctional adhesion molecule C
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin domain subtype Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype 2 Junctional adhesion molecule C
UniProtKB:F1QYW3 301
UniProtKB:A0A8M1Q7B3 301
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA jam3a-201 (1) Ensembl 2,152 nt
mRNA jam3a-202 (1) Ensembl 6,039 nt
mRNA jam3a-203 (1) Ensembl 5,647 nt
mRNA jam3a-204 (1) Ensembl 819 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-jam3a monoclonal IgG1 , k Mouse
1
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations