Gene
adrb2b
- ID
- ZDB-GENE-070410-32
- Name
- adrenoceptor beta 2, surface b
- Symbol
- adrb2b Nomenclature History
- Previous Names
-
- zgc:162188
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable beta2-adrenergic receptor activity and norepinephrine binding activity. Acts upstream of or within regulation of heart rate. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including digestive system; eye; heart; kidney; and musculature system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); disease of metabolism (multiple); kidney failure (multiple); lung disease (multiple); and open-angle glaucoma (multiple). Orthologous to human ADRB2 (adrenoceptor beta 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Beta-2-adrenoreceptor agonist, reduced response to |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adrenoceptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|
|
UniProtKB:A4QNV7
|
409 | |||
|
UniProtKB:A0A8M9PI29
|
409 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adrb2b-201
(1)
|
Ensembl | 3,764 nt |
Interactions and Pathways
No data available
Plasmids
No data available