Gene

rargb

ID

ZDB-GENE-070314-1

Name

retinoic acid receptor, gamma b

Symbol

rargb Nomenclature History

Previous Names

NR1B3-B (1)
nr1b3b (1)
RARgamma-B (1)

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and nuclear receptor transcription coactivator activity. Involved in determination of left/right symmetry; intrahepatic bile duct development; and negative regulation of BMP signaling pathway. Predicted to localize to RNA polymerase II transcription factor complex. Is expressed in several structures, including blastoderm; head; neural crest; pectoral fin; and tail bud. Orthologous to human RARG (retinoic acid receptor gamma).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 6 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

dq017621 (15 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Garnaas et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rargb Human Ortholog

No data available

Associated With rargb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000536	Nuclear hormone receptor, ligand-binding domain
Domain	IPR001628	Zinc finger, nuclear hormone receptor-type
Domain	IPR047158	Retinoic acid receptor, ligand-binding domain
Domain	IPR047159	Retinoic acid receptor, DNA-binding domain
Family	IPR001723	Nuclear hormone receptor
Family	IPR003078	Retinoic acid receptor
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type
Homologous_superfamily	IPR035500	Nuclear hormone receptor-like domain superfamily