Gene

hcrtr2

ID
ZDB-GENE-070228-3
Name
hypocretin (orexin) receptor 2
Symbol
hcrtr2 Nomenclature History
Previous Names
  • hcrtr (2)
  • hcrt receptor (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable orexin receptor activity. Acts upstream of or within circadian behavior; melatonin metabolic process; and regulation of circadian sleep/wake cycle, sleep. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain and spinal cord. Orthologous to human HCRTR2 (hypocretin receptor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hcrtr2 Human Ortholog
No data available
Associated With hcrtr2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000204 Orexin receptor family
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR004060 Orexin receptor 2
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Orexin receptor 2 Orexin receptor family
UniProtKB:A7KBS6 424
UniProtKB:A1YQE3 424
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations