Gene

gpx3

ID
ZDB-GENE-070222-3
Name
glutathione peroxidase 3
Symbol
gpx3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have glutathione peroxidase activity. Predicted to be involved in oxidation-reduction process and response to oxidative stress. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GPX3 (glutathione peroxidase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Restuadi et al., 2022
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gpx3 Human Ortholog
No data available
Associated With gpx3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR029759 Glutathione peroxidase active site
Family IPR000889 Glutathione peroxidase
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Glutathione peroxidase Glutathione peroxidase active site Thioredoxin-like superfamily
UniProtKB:A0A8M1NIR5 222
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA gpx3-201 (1) Ensembl 5,189 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations