Gene

tbx3a

ID
ZDB-GENE-070209-80
Name
T-box transcription factor 3a
Symbol
tbx3a Nomenclature History
Previous Names
  • tbx-b
  • tbx3
  • tbx3b
  • tbxb
  • zgc:158110 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic heart tube development. Predicted to localize to nucleus. Is expressed in atrioventricular canal; heart tube; notochord; pectoral fin; and retina. Human ortholog(s) of this gene implicated in ulnar-mammary syndrome. Orthologous to human TBX3 (T-box transcription factor 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Ribeiro et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tbx3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
ulnar-mammary syndrome Alliance Ulnar-mammary syndrome 181450
Associated With tbx3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018186 Transcription factor, T-box, conserved site
Domain IPR022582 Transcription factor, T-box, region of unknown function
Family IPR001699 Transcription factor, T-box
Family IPR002070 Transcription factor, Brachyury
Homologous_superfamily IPR008967 p53-like transcription factor, DNA-binding
Homologous_superfamily IPR036960 T-box superfamily
Domain Details Per Protein
Protein Length p53-like transcription factor, DNA-binding T-box superfamily Transcription factor, Brachyury Transcription factor, T-box Transcription factor, T-box, conserved site Transcription factor, T-box, region of unknown function
UniProtKB:Q29R85 279
UniProtKB:B8JKS6 689
UniProtKB:A2RUW2 689
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations