Gene
ryk
- ID
- ZDB-GENE-070209-277
- Name
- receptor like tyrosine kinase
- Symbol
- ryk Nomenclature History
- Previous Names
-
- wu:fb37b12
- wu:fi05b06
- zgc:158381
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Exhibits Wnt-protein binding activity. Involved in Wnt signaling pathway, calcium modulating pathway; convergent extension; and release of sequestered calcium ion into cytosol. Localizes to plasma membrane. Is expressed in heart tube; nervous system; notochord; post-vent region; and somite. Orthologous to human RYK (receptor like tyrosine kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008266 | Tyrosine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR003306 | WIF domain |
| Family | IPR050122 | Receptor Tyrosine Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR038677 | WIF domain superfamily |
Domain Details Per Protein
| Protein | Length | Protein kinase domain | Protein kinase-like domain superfamily | Receptor Tyrosine Kinase | Serine-threonine/tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, active site | WIF domain | WIF domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A2RRV7
|
604 | |||||||
|
UniProtKB:E7FAI5
|
632 |
Interactions and Pathways
No data available
Plasmids
No data available