Gene
coq7
- ID
- ZDB-GENE-070209-262
- Name
- coenzyme Q7 homolog, ubiquinone (yeast)
- Symbol
- coq7 Nomenclature History
- Previous Names
-
- im:7159541
- zgc:158731
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity. Predicted to be involved in several processes, including determination of adult lifespan; regulation of reactive oxygen species metabolic process; and ubiquinone biosynthetic process. Predicted to localize to mitochondrial inner membrane and nucleus. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 8. Orthologous to human COQ7 (coenzyme Q7, hydroxylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7159541 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive distal hereditary motor neuronopathy 9 | Alliance | Neuronopathy, distal hereditary motor, autosomal recessive 9 | 620402 |
| primary coenzyme Q10 deficiency 8 | Alliance | Coenzyme Q10 deficiency, primary, 8 | 616733 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ferritin-like superfamily | Ubiquinone biosynthesis protein Coq7 |
|---|---|---|---|
|
UniProtKB:A2RV27
|
223 |
Interactions and Pathways
No data available
Plasmids
No data available