Gene

celsr2

ID
ZDB-GENE-070122-2
Name
cadherin, EGF LAG seven-pass G-type receptor 2
Symbol
celsr2 Nomenclature History
Previous Names
  • celsr2l
  • fmi2 (1)
  • off-road
  • ord
  • si:rp71-11b17.1
  • si:rp71-11b17.9 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have G protein-coupled receptor activity and calcium ion binding activity. Involved in several processes, including cell-cell adhesion; epiboly involved in gastrulation with mouth forming second; and facial nucleus development. Localizes to plasma membrane. Is expressed in brain; eye; and ovary. Orthologous to human CELSR2 (cadherin EGF LAG seven-pass G-type receptor 2).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With celsr2 Human Ortholog
No data available
Associated With celsr2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020894 Cadherin conserved site
Domain IPR000203 GPS motif
Domain IPR000742 EGF-like domain
Domain IPR001791 Laminin G domain
Domain IPR001879 GPCR, family 2, extracellular hormone receptor domain
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR002049 Laminin EGF domain
Domain IPR002126 Cadherin-like
Domain IPR017981 GPCR, family 2-like
Domain IPR032471 GAIN domain, N-terminal
Family IPR000832 GPCR, family 2, secretin-like
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR015919 Cadherin-like superfamily
Homologous_superfamily IPR036445 GPCR family 2, extracellular hormone receptor domain superfamily
Domain Details Per Protein
Protein Length Cadherin conserved site Cadherin-like Cadherin-like superfamily Concanavalin A-like lectin/glucanase domain superfamily EGF-like calcium-binding domain EGF-like domain GAIN domain, N-terminal GPCR, family 2, extracellular hormone receptor domain GPCR family 2, extracellular hormone receptor domain superfamily GPCR, family 2-like GPCR, family 2, secretin-like GPS motif Growth factor receptor cysteine-rich domain superfamily Laminin EGF domain Laminin G domain
UniProtKB:F1QT64 2940
UniProtKB:F1QEP4 1271
UniProtKB:F1R6V8 85
UniProtKB:A0JBX1 2941
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations