ZFIN ID: ZDB-GENE-070122-2 |
Gene Name: | cadherin, EGF LAG seven-pass G-type receptor 2 | ||||||
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Gene Symbol: | celsr2 Nomenclature History | ||||||
Previous Names: | celsr2l, fmi2 (1), off-road, ord, si:rp71-11b17.1, si:rp71-11b17.9 (1) | ||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 22 Mapping Details/Browsers | ||||||
Description: | Predicted to have G protein-coupled receptor activity and calcium ion binding activity. Involved in several processes, including cell-cell adhesion; epiboly involved in gastrulation with mouth forming second; and facial nucleus development. Localizes to the plasma membrane. Is expressed in brain; eye; and ovary. Orthologous to human CELSR2 (cadherin EGF LAG seven-pass G-type receptor 2). | ||||||
Genome Resources: | Alliance (1), Gene:560426 (1), Ensembl(GRCz11):ENSDARG00000019726 (2) |
All Expression Data: | 3 figures from 3 publications |
Wild-type Stages, Structures: | Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult) |
Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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celsr2_unspecified | Unspecified | Unknown | Unknown | ||
rw71 | Point Mutation | Unknown | Unknown | ||
rw135 | Point Mutation | Unknown | Unknown | ||
rw166 | Point Mutation | Unknown | Unknown | ||
rw380 | Point Mutation | Unknown | Unknown | ||
sa15866 | Point Mutation | Unknown | Premature Stop | ENU |
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sa24041 | Point Mutation | Unknown | Splice Site | ENU |
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sa24043 | Point Mutation | Unknown | Premature Stop | ENU |
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sa43733 | Point Mutation | Unknown | Premature Stop | ENU |
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sa43735 | Point Mutation | Unknown | Premature Stop | ENU |
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Targeting Reagent | Created Alleles | Publications |
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MO1-celsr2 | N/A | 1 |
MO2-celsr2 | N/A | 1 |
Data: | 6 figures from 2 publications |
Observed in: |
Ontology | GO Term |
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Biological Process | cell-cell adhesion (more) |
Cellular Component | plasma membrane (more) |
Molecular Function | calcium ion binding (more) |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
celsr2-202
(1)
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3813 |
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celsr2-203
(1)
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728 |
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Browsers: UCSC, NCBI, Ensembl, ZFIN |
celsr2 Contained in: | [BAC] RP71-11B17 (1) (order this) |
celsr2 Encodes: | [EST] wz12434 |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:NM_001080577 (1) | 8826 bp |
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Genomic | GenBank:AL645789 (1) | 167635 bp | |
Polypeptide | UniProtKB:A0JBX1 (1) | 2941 aa |
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Sequence Clusters | UniGene:110394 (1) |