Gene

traf7

ID

ZDB-GENE-070112-2212

Name

TNF receptor-associated factor 7

Symbol

traf7 Nomenclature History

Previous Names

im:7149067
zgc:158391

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity. Orthologous to human TRAF7 (TNF receptor associated factor 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7149067 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Mishra-Gorur et al., 2023
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With traf7 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Cardiac, facial, and digital anomalies with developmental delay	618164

Associated With traf7 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR027370	Zinc finger, RING-type, eukaryotic
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat

Domain Details Per Protein

Protein	Length	G-protein beta WD-40 repeat	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type	Zinc finger, RING-type, conserved site	Zinc finger, RING-type, eukaryotic
UniProtKB:A1L1U9 InterPro	639

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	traf7-201 (1) Ensembl	Ensembl	3,410 nt	Select Tool ZFIN BLAST
mRNA	traf7-203 (1) Ensembl	Ensembl	3,304 nt	Select Tool ZFIN BLAST
mRNA	traf7-204 (1) Ensembl	Ensembl	2,308 nt	Select Tool ZFIN BLAST
ncRNA	traf7-002 (1) Ensembl	Ensembl	1,284 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations