Gene

cdt1

ID
ZDB-GENE-070111-1
Name
chromatin licensing and DNA replication factor 1
Symbol
cdt1 Nomenclature History
Previous Names
  • fc37h07
  • im:7158083 (1)
  • wu:fc37h07
  • wu:fi38h09 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and DNA polymerase binding activity. Involved in mitotic cell cycle. Predicted to localize to nucleus. Is expressed in several structures, including immature eye; mesoderm; proliferative region; pronephric duct; and somite. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Orthologous to human CDT1 (chromatin licensing and DNA replication factor 1).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdt1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Meier-Gorlin syndrome 4 Alliance Meier-Gorlin syndrome 4 613804
Associated With cdt1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR014939 CDT1 Geminin-binding domain-like
Domain IPR032054 DNA replication factor Cdt1, C-terminal
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length CDT1 Geminin-binding domain-like DNA replication factor Cdt1, C-terminal Winged helix DNA-binding domain superfamily
UniProtKB:F8W3F6 458
UniProtKB:E7F2R5 678
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations