Gene
hs6st1b
- ID
- ZDB-GENE-070103-2
- Name
- heparan sulfate 6-O-sulfotransferase 1b
- Symbol
- hs6st1b Nomenclature History
- Previous Names
-
- 6-ost-1b (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable heparan sulfate 6-O-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to be located in membrane. Is expressed in several structures, including hindbrain neural keel; immature eye; nervous system; pancreatic bud; and presumptive floor plate. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from Cadwallader et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 15 with or without anosmia | Alliance | {Hypogonadotropic hypogonadism 15 with or without anosmia} | 614880 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase |
|---|---|---|---|---|
|
UniProtKB:A0MGZ5
|
407 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hs6st1b-201
(1)
|
Ensembl | 1,224 nt |
Interactions and Pathways
No data available
Plasmids
No data available