Gene

hs6st1b

ID
ZDB-GENE-070103-2
Name
heparan sulfate 6-O-sulfotransferase 1b
Symbol
hs6st1b Nomenclature History
Previous Names
  • 6-ost-1b (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to enable heparan sulfate 6-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in membrane. Is expressed in several structures, including hindbrain neural keel; immature eye; nervous system; pancreatic bud; and presumptive floor plate. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from Cadwallader et al., 2006
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hs6st1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 15 with or without anosmia Alliance {Hypogonadotropic hypogonadism 15 with or without anosmia} 614880
1 - 1 of 1
Associated With hs6st1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR005331 Sulfotransferase
Family IPR010635 Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
1 - 3 of 3
Domain Details Per Protein
Protein Additional Resources Length Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase P-loop containing nucleoside triphosphate hydrolase Sulfotransferase
UniProtKB:A0MGZ5 InterPro 407
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hs6st1b-201 (1) Ensembl 1,224 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations