Gene
atoh8
- ID
- ZDB-GENE-061215-7
- Name
- atonal bHLH transcription factor 8
- Symbol
- atoh8 Nomenclature History
- Previous Names
-
- Zath6 (1)
- zgc:158314
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity; DNA-binding transcription factor activity; and protein dimerization activity. Involved in animal organ morphogenesis; regulation of neural retina development; and regulation of skeletal muscle cell differentiation. Predicted to localize to cytoplasm and nuclear speck. Is expressed in several structures, including nervous system; neural crest cell; optic cup; optic vesicle; and trunk. Orthologous to human ATOH8 (atonal bHLH transcription factor 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
| Domain | IPR032660 | Transcription factor ATOH8, basic helix-loop-helix domain |
| Family | IPR050359 | Basic helix-loop-helix transcription factors |
| Homologous_superfamily | IPR036638 | Helix-loop-helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Basic helix-loop-helix transcription factors | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Transcription factor ATOH8, basic helix-loop-helix domain |
|---|---|---|---|---|---|
|
UniProtKB:D2CLZ9
|
266 |
Interactions and Pathways
No data available
Plasmids
No data available