dhx34

ID

ZDB-GENE-061207-30

Name

DEAH (Asp-Glu-Ala-His) box polypeptide 34

Symbol

dhx34 Nomenclature History

Previous Names

si:ch211-255l12.1 (1)

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable RNA binding activity and helicase activity. Involved in negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay and nuclear-transcribed mRNA catabolic process. Acts upstream of or within chordate embryonic development and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Orthologous to human DHX34 (DExH-box helicase 34).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Anastasaki et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dhx34 Human Ortholog

No data available

Associated With dhx34 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR007502	Helicase-associated domain
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR011709	DEAD-box helicase, OB fold
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR048333	Helicase associated domain (HA2), winged-helix domain
Domain	IPR056382	DHX34-like, C2H2-type zinc finger
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase