Gene

mical2b

ID

ZDB-GENE-061207-15

Name

microtubule associated monooxygenase, calponin and LIM domain containing 2b

Symbol

mical2b Nomenclature History

Previous Names

sb:cb94
si:ch211-192p3.1
si:ch211-192p3.2
wu:fi76d02

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have NADPH:sulfur oxidoreductase activity and actin binding activity. Involved in heart looping. Predicted to localize to filamentous actin; microtubule organizing center; and nucleus. Is expressed in several structures, including cardiovascular system; digestive system; fin; mesoderm; and sensory system. Orthologous to human MICAL2 (microtubule associated monooxygenase, calponin and LIM domain containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb94 (21 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mical2b Human Ortholog

No data available

Associated With mical2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001715	Calponin homology domain
Domain	IPR001781	Zinc finger, LIM-type
Domain	IPR002938	FAD-binding domain
Domain	IPR022735	bMERB domain
Family	IPR050540	F-actin Monooxygenase Mical
Homologous_superfamily	IPR036188	FAD/NAD(P)-binding domain superfamily
Homologous_superfamily	IPR036872	CH domain superfamily

Domain Details Per Protein

Protein	Length	bMERB domain	Calponin homology domain	CH domain superfamily	F-actin Monooxygenase Mical	FAD-binding domain	FAD/NAD(P)-binding domain superfamily	Zinc finger, LIM-type
UniProtKB:A0A8M9PV03 InterPro	1656
UniProtKB:F1RA39 InterPro	1679
UniProtKB:A0A8M9P6G8 InterPro	1567
UniProtKB:A0A8M9PYF5 InterPro	1668
UniProtKB:A0A8M9PYG2 InterPro	1120
UniProtKB:A0A8M9PMT4 InterPro	1524
UniProtKB:A0A8M9PGW2 InterPro	1555
UniProtKB:A0A8M9PMS9 InterPro	1679

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mical2b-201 (1) Ensembl	Ensembl	3,363 nt	Select Tool ZFIN BLAST
mRNA	mical2b-202 (1) Ensembl	Ensembl	5,425 nt	Select Tool ZFIN BLAST
mRNA	mical2b-203 (1) Ensembl	Ensembl	4,899 nt	Select Tool ZFIN BLAST
mRNA	mical2b-204 (1) Ensembl	Ensembl	5,797 nt	Select Tool ZFIN BLAST
mRNA	mical2b-205 (1) Ensembl	Ensembl	5,728 nt	Select Tool ZFIN BLAST
mRNA	mical2b-206 (1) Ensembl	Ensembl	6,665 nt	Select Tool ZFIN BLAST
mRNA	mical2b-207 (1) Ensembl	Ensembl	3,027 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations