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ZIRC
ZFIN ID: ZDB-GENE-061108-4
Gene Name: nucleotide-binding oligomerization domain containing 2
Gene Symbol: nod2
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: card15 (1), NLR-A2 (1)

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits protein heterodimerization activity. Involved in defense response to bacterium; defense response to virus; and regulation of transcription, DNA-templated. Localizes to the cytoplasm. Human  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029339Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • mn68 Small Deletion Unknown Unknown TALEN
    sa10156 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18880 Point Mutation Unknown Premature Stop ENU
    sa21011 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nod2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Blau syndrome Blau syndrome 186580
    inflammatory bowel disease 1 {Inflammatory bowel disease 1, Crohn disease} 266600
    {Yao syndrome} 617321
    {Psoriatic arthritis, susceptibility to} 607507
    DISEASE ASSOCIATED WITH nod2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process defense response to virus (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein heterodimerization activity (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA nod2-002 (1) 985
    mRNA nod2-201 (1) 3780
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nod2 No data available
    MARKER RELATIONSHIPS
    nod2Contained in: [Fosmid] CH1073-91I12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001328044 (1)
    Genomic GenBank:CU929130 (1) 32076bp
    Select Tool
    Polypeptide UniProtKB:F8W3K2 (1) 980aa
    Sequence Clusters UniGene:93177 (1)
    Sequence Information (all 16)
    ORTHOLOGY for nod2 (Chr: 7)
    CITATIONS (46)