Gene

agpat2

ID
ZDB-GENE-061103-541
Name
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
Symbol
agpat2 Nomenclature History
Previous Names
  • zgc:153984
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidic acid biosynthetic process. Predicted to localize to endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 1 and lipodystrophy. Orthologous to several human genes including AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Zhao et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With agpat2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital generalized lipodystrophy type 1 Alliance Lipodystrophy, congenital generalized, type 1 608594
Associated With agpat2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002123 Phospholipid/glycerol acyltransferase
Domain IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase
Domain Details Per Protein
Protein Length 1-acyl-sn-glycerol-3-phosphate acyltransferase Phospholipid/glycerol acyltransferase
UniProtKB:A0JMM2 271
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations