Gene
tpcn2
- ID
- ZDB-GENE-061103-202
- Name
- two pore segment channel 2
- Symbol
- tpcn2 Nomenclature History
- Previous Names
-
- fi42c05
- im:7140344
- wu:fi42c05
- zgc:152898
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have NAADP-sensitive calcium-release channel activity and voltage-gated calcium channel activity. Involved in calcium-mediated signaling; regulation of myotome development; and skeletal myofibril assembly. Predicted to localize to lysosomal membrane. Is expressed in slow muscle cell. Orthologous to human TPCN2 (two pore segment channel 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7140344 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| [Skin/hair/eye pigmentation 10, blond/brown hair] | 612267 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ion transport domain | Two pore channel protein 2 | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0JMD4
|
774 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available