Gene
deptor
- ID
- ZDB-GENE-061013-453
- Name
- DEP domain containing MTOR-interacting protein
- Symbol
- deptor Nomenclature History
- Previous Names
-
- depdc6
- fd14h03
- fi11e09
- wu:fd14h03
- wu:fi11e09
- zgc:152943
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity; guanyl-nucleotide exchange factor activity; and protein serine/threonine kinase inhibitor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; negative regulation of TORC1 signaling; and negative regulation of TORC2 signaling. Predicted to act upstream of or within intracellular signal transduction and negative regulation of TOR signaling. Predicted to be active in plasma membrane. Orthologous to human DEPTOR (DEP domain containing MTOR interacting protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000591 | DEP domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR037335 | DEP domain-containing mTOR-interacting protein, DEP domain 1 |
| Domain | IPR037336 | DEP domain-containing mTOR-interacting protein, DEP domain 2 |
| Family | IPR051832 | Regulators of mTOR signaling and Rac activation |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | DEP domain | DEP domain-containing mTOR-interacting protein, DEP domain 1 | DEP domain-containing mTOR-interacting protein, DEP domain 2 | PDZ domain | PDZ superfamily | Regulators of mTOR signaling and Rac activation | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BKU4
|
407 | ||||||||
|
UniProtKB:Q08BQ7
|
348 | ||||||||
|
UniProtKB:A0A8M1NBQ2
|
365 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
deptor-201
(1)
|
Ensembl | 2,648 nt | ||
| mRNA |
deptor-202
(1)
|
Ensembl | 679 nt | ||
| mRNA |
deptor-203
(1)
|
Ensembl | 2,019 nt | ||
| mRNA |
deptor-204
(1)
|
Ensembl | 2,648 nt |
Interactions and Pathways
No data available
Plasmids
No data available