Gene
lpar6a
- ID
- ZDB-GENE-061013-343
- Name
- lysophosphatidic acid receptor 6a
- Symbol
- lpar6a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Exhibits lysophosphatidic acid receptor activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and angiogenesis. Localizes to integral component of plasma membrane. Human ortholog(s) of this gene implicated in hypotrichosis. Orthologous to human LPAR6 (lysophosphatidic acid receptor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kalén et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypotrichosis 8 | Alliance | Hypotrichosis 8 | 278150 |
| hypotrichosis 8 | Alliance | Woolly hair, autosomal recessive 1, with or without hypotrichosis | 278150 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|
|
UniProtKB:Q08BG4
|
357 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lpar6a-201
(1)
|
Ensembl | 1,928 nt | ||
| mRNA |
lpar6a-202
(1)
|
Ensembl | 1,082 nt |
Interactions and Pathways
No data available
Plasmids
No data available